Harmonisation of Endocrine Dynamic Testing -Adult (HEDTA)
Neuroendocrine tumours, cancer related endocrinopathy
Male reproductive endocrinology
Female reproductive endocrinology
Download Harmonisation of Endocrine Dynamic Testing -Adult (HEDTA)
The HEDTA manual is a joint initiative from ESA/AACB/RCPA and is freely available as a resource for Endocrinologists and Biochemists. The information provided is a guide only and needs to be verified by individual clinicians and laboratories prior to use. Modifications might be required according to local procedures (e.g., patient consent, sample type, name of test set, collection, interpretation and reporting procedures). Queries can be directed to the chair of the HEDTA working party.
Adrenal incidentalomas
European Society of Endocrinology Clinical Guidelines 2023
Congenital adrenal hyperplasia
US Endocrine Society Clinical Guideline 2018
https://www.endocrine.org/clinical-practice-guidelines/adrenal
Primary aldosteronism
US Endocrine Society Clinical Guideline 2016
https://www.endocrine.org/clinical-practice-guidelines/primary-aldosteronism
Japan Endocrine Society Clinical Guideline 2021
https://www.jstage.jst.go.jp/article/endocrj/69/4/69_EJ21-0508/_pdf/-char/en
Adrenal insufficiency
US Endocrine Society Clinical Guideline 2016
https://www.endocrine.org/clinical-practice-guidelines/primary-aldosteronism
Japan Endocrine Society Clinical Guideline 2016
https://www.jstage.jst.go.jp/article/endocrj/63/9/63_EJ16-0242/_pdf
British Society for Paediatric Endocrinology and Diabetes 2020 (free to access)
https://www.bsped.org.uk/clinical-resources/bsped-adrenal-insufficiency-consensus-guidelines/
European expert consensus statement on diagnosis, treatment and follow-up (2014)
https://onlinelibrary.wiley.com/doi/epdf/10.1111/joim.12162
European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: Diagnosis and Therapy of Glucocorticoid-induced Adrenal Insufficiency 2024
https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae250/7667842?login=false
Cushing’s syndrome/ Cushing’s disease
US Endocrine Society Clinical Guideline
https://www.endocrine.org/clinical-practice-guidelines/treatment-of-cushing-syndrome
https://www.endocrine.org/clinical-practice-guidelines/diagnosis-of-cushing-syndrome
Pituitary Society Consensus Guideline (2021)
https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00235-7/abstract
Adrenocortical carcinoma
European Endocrine Society (2018)
Osteoporosis
US Endocrine Society Clinical Guideline for Women (2020)
https://www.endocrine.org/clinical-practice-guidelines/osteoporosis-in-postmenopausal-women
US Endocrine Society Clinical Guideline for Men (2012)
https://www.endocrine.org/clinical-practice-guidelines/osteoporosis-in-men
RACGP Osteoporosis Guidelines (2024)
Healthy Bones Australia Exercise Prescription (2024)
https://healthybonesaustralia.org.au/wp-content/uploads/2024/02/hba-ex-presc-final-compressed.pdf
International Osteoporosis Foundation – Trabecular bone score update (2023)
https://link.springer.com/article/10.1007/s00198-023-06817-4
European Consensus Statement on the osteoporosis management in chronic kidney disease (2020)
https://academic.oup.com/ndt/article/36/1/42/5938134?login=false
Paget’s disease
US Endocrine Society Clinical Guideline (2014)
https://www.endocrine.org/clinical-practice-guidelines/pagets-disease-of-bone
UK Paget’s Association, European Calcified Tissue Society, Internationa Osteoporosis Foundation – Clinical Guideline (2019)
https://paget.org.uk/health-and-research-professionals/clinical-guideline/
Hyperparathyroidism
Endocrine Society of Australia, Australian & New Zealand endocrine surgeons, and the Australian and New Zealand bone and mineral society position statement
Hypoparathyroidism
European Society of Endocrinology (2015)
American Thyroid Association Guidelines
https://www.thyroid.org/professionals/ata-professional-guidelines/
includes guidelines on thyroid nodules, thyroid cancer, hypo- or hyperthyroidism, thyroid disease in pregnancy and postpartum
European Thyroid Association Guidelines
https://www.eurothyroid.com/guidelines/eta_guidelines.html
includes guidelines on both adults and pediatric population regarding thyroid nodules, thyroid cancer, hypo- or hyperthyroidism, post-iodine contract and amiodarone induced thyroid dysfunction, thyroid disorders for assisted reproduction and pregnancy, Graves’ orbitopathy
Pituitary incidentaloma
US Endocrine Society Clinical Guideline (2011)
https://www.endocrine.org/clinical-practice-guidelines/pituitary-incidentaloma
European Society of Endocrinology – Guideline for functioning and non-functioning pituitary adenoma in pregnancy (2021)
Hypopituitarism
US Endocrine Society Clinical Guideline (2016)
https://www.endocrine.org/clinical-practice-guidelines/hormone-replacement-in-hypopituitarism
Pituitary tumours
European Society of Endocrinology Clinical Guideline (2018)
GH deficiency
The Endocrine Society of Australia (ESA) holds the view that adults with growth hormone (GH) deficiency are not normal and have impaired health. Such patients have a characteristic clinical syndrome which includes abnormal body composition, reduced physical fitness, increased cardiovascular risk factors, osteopaenia and impaired psychological function. Based on evidence that GH replacement is beneficial, the ESA endorses the principle that adults with GH deficiency should be considered for GH replacement therapy. Such patients must be accurately diagnosed. Patients with a history of organic hypothalamic-pituitary disease exhibiting characteristics of the GH deficient syndrome and who fulfil rigorous diagnostic criteria should be considered eligible for treatment.
The ESA recommends the guidelines of the Endocrine Society for the diagnosis, treatment and monitoring of GH deficient patients on GH therapy. The ESA does not support the use of GH in adults without GH deficiency.
https://academic.oup.com/jcem/article/96/6/1587/2833853
US Endocrine Society Clinical Guideline (2016): Pharmacological management of obesity
https://www.endocrine.org/clinical-practice-guidelines/pharmacological-management-of-obesity
European Society of Endocrinology (2020): Endocrine work-up in obesity
https://academic.oup.com/ejendo/article/182/1/G1/6653910?searchresult=1
Australian Obesity Management Algorithm (2020)– endorsed by Australian Diabetes Society and Australian & New Zealand Obesity Society
https://www.diabetessociety.com.au/guideline/obesity/
European Society of Endocrinology (2016): long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma
European Society of Endocrinology (2022): Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition
Hypogonadism
US Endocrine society (2018): Testosterone therapy for hypogonadism
https://www.endocrine.org/clinical-practice-guidelines/testosterone-therapy
European Society of Endocrinology (2023): Testosterone therapy in older man
European Society of Endocrinology (2020): functional hypogonadism
Endocrine Society of Australia position statement (2016) – part 1 and 2
Male sexual dysfunction
Healthy male (2019): Erectile dysfunction and treatment
Klinefelter Syndrome
European Society of Endocrinology (2020)
Turner syndrome
European Society of Endocrinology (2017)
Polycystic ovary syndrome
International PCOS Guideline (2023)– endorsed by US Endocrine Society, European Society of Endocrinology
https://www.monash.edu/medicine/mchri/pcos/guideline
Hypothalamic amenorrhea
US Endocrinology Society (2017)
https://www.endocrine.org/clinical-practice-guidelines/hypothalamic-amenorrhea
Menopause
US Endocrinology Society (2015)
https://www.endocrine.org/clinical-practice-guidelines/treatment-of-menopause
US endocrinology Society (2014): Androgen therapy in women
https://www.endocrine.org/clinical-practice-guidelines/androgen-therapy-in-women
Australasian Menopause Society
https://www.menopause.org.au/hp/management
US Endocrine Society (2017)
https://www.endocrine.org/clinical-practice-guidelines/gender-dysphoria-gender-incongruence
AusPATH Standards of Care for Gender Affirming Hormone Therapy (2022)
AusPATH Position Statement (2019)
During the 2017 Australian Professional Association for Trans Health Biennial Conference, the need for an Australian‐based gender‐affirming hormone‐treatment pathway was highlighted. A working group chaired by Dr Ada Cheung, reviewed relevant evidence, published guidelines and expert opinion to develop Australian guidelines. The guidelines were also informed by survey responses of Australian transgender or gender diverse adult individuals, to ascertain health needs, and current Australian prescribing patterns among the AusPATH members. The resulting guidelines provide specific recommendations for the hormonal and related management of TGD individuals aged over 18 years for Australian medical practitioners.
Endocrine Society of Australia
145 Macquarie Street
Sydney. NSW. 2000
Email: ijohnson@endocrinesociety.org.au
The Endocrine Society of Australia acknowledges the Australian Aboriginal and Torres Strait Islander peoples as the first inhabitants of the nation and the traditional custodians of the lands where we live, learn and work. We pay our respects to their Elders past, present and emerging.
